An over-the-counter combination of several plant extracts Oleuropein, Kudzu plant extract, Perilla leaf, Holy Basil, Ginseng, Amur bark and Propolis has recently been shown to lead to powerful fat loss results when administered in all types of experimental animals. This is a completely safe combination of natural factors. It’s commonly referred to as Oleuperill – an amalgamation of the Oleuropein and Perilla words.
the reason this combination of ingredients was tested in laboratory animals as opposed to humans is not safety. It’s just that using an animal model leads to much better data and much clearer numbers. It’s much easier to control the dietary and caloric intake of mice than it is to make a group of humans stick precisely to a pre-determined dietary regime.
Most of the ingredients in this formulation have been used and popularized for weight loss before – but it’s their synergistic effect that led to the surprising amount of fat, which both the animals and the people burned in the experiments. Take any random ingredient out of the equation – propolis for example, and the results are no longer as good.
The Oleuperill formula seems to stimulate the adipocytes to release their fatty acid stores. At first glance it seems like this might boost cholesterol levels, but in the experiments, the researchers found the opposite to be true – the LDL levels dropped, while HDL (‘good’ cholesterol) levels modestly increased.
How Well Does Oleuperill Work When Compared to Caloric Restriction?
This was the most remarkable discovery – Oleuperill seems to work just as well as caloric restriction, at least in the short-term. And we already know that long-term caloric restriction is not really a feasible strategy for most people. Periods of increased hunger (‘hunger pangs’) seems to maintain the long-term caloric balance and prevent any weight loss in the majority of people. This is due to up-regulation of various processes in the adipose tissue and increased insulin levels.